临床影像、手术导航、分子影像

国家自然科学基金委重大科研仪器研制专项,  “基于磁纳米粒子非线性响应的活体动物三维融合成像设备“ 2021.1-2025.12，7796万元，子课题                                        国家自然科学基金委地区联合重点项目，“脑胶质瘤新增分子分型及疗效预后的多组学融合智能影像研究”，2022.1-2025.12, 300万，子课题                                        国家自然科学基金委青年项目，”M1/M2巨噬细胞在骨髓间充质干细胞治疗心肌梗死过程中的作用研究“， 2014.1-2016.12，23万元，主持                                            北京市自然科学基金-海淀原始创新联合基金，”PET/NIR-II双模态成像引导的关节假体周围感染智能诊疗关键技术研究“，2023.11-2026.11，100万，子课题                                        京津冀基础研究专项，"活体术中脑胶质瘤诊断及边界检测技术的研究"，2019.10-2022.9，60万，主持(北京地区）

1.Bo Wang#, Chu Tang#, En Lin#, Xiaohua Jia#, Ganyuan Xie, Peiping Li, Decheng Li, Qiyue Yang, Xiaoyong Guo, Caiguang Cao, Xiaojing Shi , Baojia Zou, Chaonong Cai, Jie Tian*, Zhenhua Hu*, Jian Li*. NIR-II fluorescence-guided liver cancer surgery by a small molecular HDAC6 targeting probe. EBioMedicine. 2023 Dec:98:104880.（SCI IF=11.205）                                    2.Xiaoyong Guo#, Changjian Li#, Xiaohua Jia#, Yawei Qu, Miaomiao Li，Caiguang Cao, Zhenhua Hu*, Haifeng liu*, Jie tian*. NIR-II Fluorescence Imaging-Guided Colorectal Cancer Surgery Targets CEACAM5 by Nanobody. EBioMedicine. 2023 Mar:89:104476.（SCI IF=11.205）                                                                                                                                 3.Xiaohua Jia, Guodong Shen, Jia Jia, Yan Zhang, Dan Zhang, Wanjun Li, Jianjun Zhang, Xinglu Huang, Jie Tian. Lineage Tracing and Molecular Real-Time Imaging of Cancer Stem Cells. Biosensors (Basel). 2022 Sep 1;12(9):703. （SCI IF=5.743）                                                                                                                                                                               4.Bing Jiang#, Xiaohua Jia#, Tianjiao Ji, Meng Zhou, Jiuyang He, Kun Wang, Jie Tian*, Xiyun Yan*, Kelong Fan*. Multi-modality ferritin nanocages for early theranostics of tumors via enhanced active targeting by tumor-associated inflammation. SCIENCE CHINA Life Sciences. 2022 Feb;65(2):328-340（SCI IF=10.420）                                                                        5. Chunhua Luo, Dongyuan Lü, Lu Zheng, Fan Zhang, Xiao Zhang, Shouqin Lü, Chen Zhang, Xiaohua Jia, Xinyu Shu, Peiwen Li, Zhan Li, Mian Long. Hepatic differentiation of human embryonic stem cells by coupling substrate stiffness and microtopography. Biomater Sci. 2021 May 18;9(10):3776-3790. （SCI IF=6.843）                                                            6.Xiaohua Jia#, Kelong Fan#, Ruofei Zhang, Dan Zhang, Jianjun Zhang, Yuan Gao, Tao Zhang, Wanjun Li, Junlai Li1*, Xiyun Yan*, and Jie Tian*. Precise visual distinction of brain glioma from normal tissues via targeted photoacoustic and fluorescence navigation. Nanomedicine: NBM. 2020;27:102204.（SCI IF=6.458）                                                                                7.Bin Yu, Andrew Steptoe, Kaijun Niu, Xiaohua Jia*. Social Isolation and Loneliness as Risk Factors for Grip Strength Decline Among Older Women and Men in China. J Am Med Dir Assoc. 2020 25;S1525-8610(20)30541-7. （SCI IF=4.669）                                                                                                                                                                                         8.Bin Yu*, Andrew Steptoe, DPhil, Kaijun Niu, Xiaohua Jia. Social isolation, rather than loneliness, is associated with cognitive decline in older adults: the China health and retirement longitudinal study. Psychological Medicine. 2020. Apr 27;1-8（SCI IF=5.641）                                                                                                                                                       9.Lu Zheng, Dongyuan Lv, Fan Zhang, Min Xing, Xiaoya Wang, Xiaohua Jia, Xinyu Shu, Peiwen Li, Shouqin Lv, Jiang Chang, Mian Long*. Regulation of hepatic differentiation of human embryonic stem cells by calcium silicate extracts for liver injury repairing. Applied Materials Today. 2020. （SCI IF=8.352）                                                                                 10.Kelong Fan#*, Xiaohua Jia#, Meng Zhou#, Kun Wang, João Conde, Jiuyang He, Jie Tian*, Xiyun Yan*. Ferritin nanocarrier traverses the blood brain barrier and kills glioma. Acs Nano. 2018; 12(5): 4105-4115. （SCI IF=18.027）                                                                                                                                                                                                    11.Xiao Wang, Liang Xie, Janet Crane, Gehua Zhen, Fengfeng Li, Ping Yang, Manman Gao, Ruoxian Deng, Yiguo Wang, Xiaohua Jia, Cunyi Fan, Mei Wan, and Xu Cao*. Aberrant TGF-β activation in bone tendon insertion induces enthesopathy-like disease. J Clin Invest. 2018; 128(2): 846-860. （SCI IF=13.251）